An exploratory epidemiological-style analysis examining geographic variation in environmental radiation measurements and what these patterns can — and cannot — tell us about radiation-related cancer risk during future space missions.
Explore the Research ↓This project began with a broader question about the relationship between radiation exposure and cancer risk during long-duration spaceflight.
My original goal was to explore this question using evidence from astronauts and other exposed populations. However, I encountered an important limitation: the number of astronauts with long-duration deep-space radiation exposure is very small.
This creates a challenge for epidemiological research. When a sample is very small, it becomes difficult to identify reliable patterns, estimate risk with confidence, or determine whether an observed relationship is meaningful.
Because the astronaut population was too small for the type of epidemiological analysis I wanted to explore, I changed the scope of the project. I conducted an exploratory epidemiological-style analysis using environmental radiation-monitoring data from four U.S. locations.
The environmental dataset provided thousands of radiation measurements, giving me a larger dataset in which to examine geographic differences, distributions, temporal patterns, and statistical relationships.
This approach does not directly measure cancer risk in astronauts. Instead, it allowed me to investigate radiation measurements using statistical and epidemiological concepts while recognizing the limitations of the available evidence.
As scientists develop plans for longer missions to the Moon and Mars, radiation exposure remains one of the major health concerns of deep-space exploration.
How does radiation exposure relate to cancer risk, and what can environmental radiation measurements tell us about radiation exposure relevant to long-duration spaceflight?
Ionizing radiation can damage DNA, and accumulated or incorrectly repaired DNA damage can contribute to cancer. However, directly studying cancer risk in astronauts is difficult because relatively few people have experienced long-duration deep-space missions.
This project therefore combines background research on radiation and cancer with an exploratory analysis of 2025 environmental radiation-monitoring data from four U.S. locations. The environmental analysis was chosen as an alternative approach after recognizing that the small number of astronauts with long-duration deep-space exposure makes direct epidemiological analysis of astronaut cancer outcomes difficult.
Ionizing radiation has enough energy to remove electrons from atoms and can damage biological molecules, including DNA. Cells have repair systems, but repair is not always perfect.
DNA damage does not automatically cause cancer. Cells can repair damage, and heavily damaged cells may die. However, mutations affecting genes that control cell growth and division can sometimes contribute to cancer.
Extremely energetic particles originating outside our solar system. They are continuously present and can be difficult to shield against.
Bursts of energetic particles released by the Sun that can temporarily increase radiation levels around a spacecraft.
Charged particles trapped by Earth's magnetic field in regions known as the Van Allen radiation belts.
Earth's atmosphere and magnetic field provide important protection from parts of the space radiation environment.
Scientists have strong evidence that sufficiently high doses of ionizing radiation can increase cancer risk. Evidence comes from populations including atomic-bomb survivors, radiation-exposed workers, patients receiving certain radiation treatments, and other exposed groups.
Understanding the risks associated with relatively low doses is more difficult. Cancer is influenced by many factors, including age, genetics, smoking, diet, ultraviolet radiation, occupation, lifestyle, and other environmental exposures.
The Linear No-Threshold model is one approach used to estimate radiation-related cancer risk. Under this model, risk is assumed to increase approximately linearly with radiation dose, with no dose considered completely risk-free. However, the LNT model is a risk-estimation model rather than a direct prediction of what will happen to every individual.
Researchers have studied early NASA astronauts to investigate whether estimated space-radiation exposure was associated with cancer mortality. These studies are valuable but limited by the small number of astronauts and relatively few cancer deaths.
The International Nuclear Workers Study included approximately 309,932 workers from France, the United Kingdom, and the United States. Researchers found that mortality from solid cancer increased as cumulative radiation dose increased, although uncertainty was greater at relatively low doses.
Occupational radiation exposure is not identical to deep-space radiation. Space radiation includes galactic cosmic rays and solar particle events with different physical characteristics.
Epidemiology investigates patterns of health-related exposures and outcomes across populations. In this project, environmental radiation measurements represent the exposure-related variable being investigated, while location serves as the population-level comparison.
Because this dataset does not contain individual cancer diagnoses, mortality, medical histories, or individual radiation exposure, this study cannot estimate cancer risk directly. Instead, it represents a small exploratory analysis of environmental radiation exposure patterns.
Before comparing radiation levels between locations, I evaluated the size, completeness, and observation periods of each dataset. I examined the number of observations, missing radiation measurements, missing timestamps, negative measurements, and the dates and times covered by each monitoring station.
The monitoring periods were not identical across all four locations. Phoenix, Miami, and Seattle had observations beginning in January 2025, while Edison began in March 2025. All four datasets extended through December 31, 2025. This difference is an important limitation because Edison contains fewer months of observations.
After evaluating the datasets, I examined the distribution of environmental radiation measurements at each location. The primary descriptive measure was the mean dose-equivalent rate, measured in nanosieverts per hour (nSv/h).
Phoenix had the highest mean dose-equivalent rate at 85.21 nSv/h, followed by Miami at 47.84 nSv/h, Edison at 40.81 nSv/h, and Seattle at 27.07 nSv/h. The distributions also differed in their ranges and overall spread.
Background radiation is not exactly the same everywhere. Possible factors include altitude, geology, naturally radioactive materials in soil and rocks, atmospheric conditions, and geography. However, the dataset alone cannot determine exactly why one location had higher measurements than another.
| Location | Mean Dose-Equivalent Rate |
|---|---|
| Phoenix, Arizona | 85.21 nSv/h |
| Miami, Florida | 47.84 nSv/h |
| Edison, New Jersey | 40.81 nSv/h |
| Seattle, Washington | 27.07 nSv/h |
The study was designed as a cross-sectional, exploratory comparison of environmental radiation measurements across four U.S. locations. The primary exposure-related variable was dose-equivalent rate, while geographic location was the primary comparison variable.
Because the study used environmental monitoring data rather than individual-level health records, the analysis focuses on differences in measured radiation rather than individual cancer outcomes.
The primary variable was dose-equivalent rate, measured in nanosieverts per hour (nSv/h). Descriptive statistics included the mean, standard deviation, median, interquartile range, minimum, maximum, and upper percentiles.
A Kruskal-Wallis test was used to compare radiation measurements among the four locations, followed by pairwise Mann-Whitney U tests with Bonferroni correction.
Statistical tests were used to determine whether the observed radiation measurements differed significantly among the four study locations.
The Kruskal-Wallis test provided strong statistical evidence that the distributions of radiation measurements were not the same across all four locations.
The test provides evidence that at least one location had a different pattern of radiation measurements from the others.
Pairwise Mann-Whitney U tests were then performed between all six pairs of locations. These tests compare locations two at a time and are useful when the data may not follow a normal distribution.
All pairwise comparisons produced extremely small p-values, and all remained statistically significant after Bonferroni correction.
An extremely small p-value does not mean that the true p-value is literally zero. It indicates that the observed differences would be very unlikely under the assumption that the groups had the same distributions.
The extremely small p-values are partly related to the very large number of observations. With thousands of measurements per location, even relatively small differences can produce very small p-values.
These findings support an association between geographic location and the distribution of measured environmental radiation in this dataset. They should not be interpreted as evidence that geographic location itself causes differences in radiation levels, or that the differences directly translate into differences in cancer risk.
Because six pairwise statistical tests were performed, there was a greater chance of obtaining a statistically significant result simply by chance. The Bonferroni correction makes the significance requirement stricter to account for these multiple comparisons.
Because statistical significance does not explain the magnitude of the difference, I calculated epsilon-squared as an effect-size measure for the Kruskal-Wallis test.
The estimated epsilon-squared effect size was approximately 0.928, indicating a very large difference in the distributions of measurements among the locations.
This suggests that the location groups were very different within this environmental radiation dataset.
The value of 0.928 does not mean that 92.8% of cancer risk is caused by location or radiation. The effect size describes the differences observed in this environmental dataset.
Miami contained 16 measurements of 0 nSv/h out of 7,349 observations. These represented approximately 0.218% of the Miami dataset.
While analyzing the data, Miami had a minimum measurement of 0 nSv/h. This was unusual because nearly all of the surrounding measurements were around 48 nSv/h.
Instead of immediately removing these measurements, I tested how much they affected the results.
Removing the zero measurements changed the Miami average by approximately 0.10 nSv/h. Therefore, removing the zero measurements had very little effect on the overall Miami average.
The dataset alone cannot determine whether these zero values represent missing measurements, invalid measurements, a detector problem, or a data-recording issue.
Importantly, the Kruskal-Wallis result also remained highly significant when the Miami zero measurements were removed.
I also examined the average radiation measurement by month. The analysis showed that radiation levels varied over the year, but the pattern differed among locations.
Phoenix monthly averages ranged from approximately 82.74 to 89 nSv/h, while Seattle ranged from approximately 25.97 to 28.15 nSv/h.
This shows that environmental radiation is not exactly the same throughout the year. However, these monthly patterns alone cannot tell us what environmental factor caused the changes.
I also examined the average radiation measurement by hour of the day. This was done to identify possible patterns in radiation levels throughout the day.
However, since environmental conditions, monitoring stations, and sampling patterns can be different at each location, these hourly differences should only be viewed as patterns in the data. They do not prove that a specific environmental factor caused the changes.
The datasets also included gamma count-rate measurements from the detector variables. I examined the relationship between dose-equivalent rate and gamma count rates.
For example, Edison showed fairly strong positive relationships with several gamma count-rate measurements, including R05 (r = 0.789), R06 (r = 0.784), and R07 (r = 0.791).
Seattle also showed positive relationships with most of the gamma count-rate measurements.
These results suggest that dose-equivalent rate and gamma count rates often increased or decreased together. However, correlation does not prove that one measurement caused the other to change.
Differences in correlation between locations also suggest that detector measurements may provide additional information that could be studied in future research.
I also examined higher-percentile measurements to identify the upper portion of each location's distribution.
These results show that Phoenix had the highest typical radiation measurements as well as the highest measurements in the upper portion of the data. Edison and Phoenix also had maximum measurements that were much higher than their usual measurements.
These higher measurements are worth investigating, but one high measurement does not necessarily mean that the exposure was dangerous or that it increased cancer risk.
Factors such as how long the exposure lasted, the accuracy of the measurement, and the total amount of radiation exposure would need to be considered.
A future Mars mission could expose astronauts to the deep-space radiation environment for months during the journey to Mars, during time on the Martian surface, and during the return trip.
Spacecraft materials can reduce radiation exposure, but additional shielding increases spacecraft mass.
Hydrogen-rich materials such as water can potentially be positioned around crew areas as part of radiation protection.
Food and other materials already required for a mission could also contribute to shielding around crew living areas.
Specially protected areas could provide additional protection during intense solar particle events.
The environmental analysis demonstrates geographic differences in measured radiation. It does not directly measure cancer outcomes or individual radiation exposure.
There are relatively few astronauts with long-duration deep-space exposure.
Occupational radiation exposure is not identical to deep-space radiation.
Monitoring stations measure environmental conditions rather than individual human exposure.
Cancer is influenced by age, genetics, smoking, UV radiation, lifestyle, occupation, and other factors.
Cancer can develop many years after radiation exposure, requiring long-term follow-up.
Edison began in March 2025 while the other three locations began in January 2025.
The environmental dataset does not contain cancer diagnoses, mortality, or individual medical information.
The evidence provides scientific reason to be concerned about radiation exposure while also showing why the exact cancer risk from deep-space radiation remains difficult to determine.
One of the most important outcomes of this project was methodological. I began with the goal of exploring radiation and cancer risk in the context of astronauts, but the limited number of astronauts with long-duration deep-space exposure made a direct epidemiological analysis difficult. Rather than treating a small sample as sufficient evidence, I changed the approach and developed an exploratory analysis using environmental radiation data.
This environmental study found substantial differences in measured radiation levels among four U.S. locations during 2025. Phoenix had the highest average dose-equivalent rate, while Seattle had the lowest.
The statistical analysis also provided strong evidence that the distributions of measured environmental radiation differed among the four locations. Pairwise comparisons remained statistically significant after Bonferroni correction.
However, these results do not demonstrate that people living in locations with higher environmental measurements have higher cancer rates. The dataset does not contain individual radiation exposure, cancer outcomes, age, sex, smoking history, occupation, medical history, or long-term follow-up.
How can scientists better estimate and reduce the long-term health risks of radiation during missions beyond Earth's protective magnetic field?
The findings of this project suggest that radiation measurements can vary substantially across environments, but environmental measurements on Earth cannot be directly substituted for measurements of deep-space radiation exposure.
Future research will require better astronaut health datasets, improved models of space-radiation exposure, and continued investigation of how different types of radiation affect human biology.
Ultimately, protecting astronauts from radiation will require both better evidence about long-term health effects and practical strategies for reducing exposure during missions to the Moon, Mars, and beyond.
This study does not show that higher environmental radiation causes higher cancer risk. Instead, it demonstrates how epidemiological and statistical methods can be used to investigate radiation patterns while carefully distinguishing statistical evidence from conclusions about human health.